Can You Overdose on Flexeril? Side Effects & Symptoms

Can You Overdose on Flexeril? Side Effects & Symptoms

For people who feel they’re addicted to Flexeril, treatment will look similar to other substances of abuse. That data suggests that Flexeril abuse is relatively common. TheU.S. Drug Enforcement Administration says that emergency room visits due to Flexeril rose 101% over a six-year period.

Cyclobenzaprine, like other muscle relaxants, is only used orally. In tablet form and extended-release capsular forms, their definitive mechanism of action is still unclear; however, the drug is considered to act on the brain stem. It works to seize the motor transmission to skeletal muscles by putting a stop to alpha and gamma neurons of the transmission pathway. However, the full effects are different for everyone especially if it’s taken with other drugs. These treatments should be administered by a licensed physician only.

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Animal studies indicate that cyclobenzaprine does not act at the neuromuscular junction or directly on skeletal muscle. Evidence suggests that the net effect of cyclobenzaprine is a reduction of tonic somatic motor activity, influencing both gamma (γ) and alpha (α) motor systems. In order to protect against the rare but potentially critical manifestations described above, obtain an ECG and immediately initiate cardiac monitoring. Protect the patient’s airway, establish an intravenous line and initiate gastric decontamination.

When those cells relax and release, movement returns, and pain tends to fade. Most people feel sleepy while taking Flexeril, and they don’t move around much. If you or a loved one is struggling with abusing muscle relaxers you can find relief. Reach out to one of our addiction treatment specialists today to learn more about your options. Cyclobenzaprine can also induce dangerous drug interactions, especially with MAO inhibitors. Also, its use with barbiturates, benzodiazepines, and verapamil have shown a greater risk of adverse effects.

FAQs About Cyclobenzaprine

They will likely recommend gradually reducing your dose over time in order to avoid any uncomfortable side effects such as nausea or dizziness. You should also inform your doctor if you feel like the medication isn’t working anymore, or if you experience any adverse side effects from taking it. Flexeril addiction is the physical or psychological dependence on the drug. People who abuse Flexeril may experience withdrawal symptoms after stopping use, such as anxiety or insomnia. Long-term use of Flexeril can lead to chemical dependency and even overdose, so its removal from the body can pose a risk to users.

You should not take more Cyclobenzaprine than prescribed at any time. Cyclobenzaprine is used to help relax muscles, as well as relieve pain, stiffness, or discomfort. This pain solved is usually caused by strains or injuries to your muscles. It should only be used for two to three weeks at a time because you can too take much of the drug. Taking Flexeril in the recommended dosage and for the right length of time should pose little to no risk of dependence or addiction forming. Abusing the drug in higher doses or combining it with other central nervous system depressants like benzodiazepines increases the risk of addiction as well as the potential for overdose.

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Your doctor will write the number of refills authorized on your prescription. “Somnus Therapy has really helped me beat insomnia and bring happiness back to my life, what else can I say.” Cyclobenzaprine comes in both short-acting tablets and long-acting capsules. Your doctor may prescribe you 5 mg, 7.5 mg, or 10 mg depending on the reason, your medical history, and other factors like age, weight, and gender. Mood changes and physical distress are causes for immediate concern, and medical attention should be immediately sought.


If you start to feel sick, it takes some time for the rest of the drug to stop working. The first step in treating any type of substance use disorder is to seek a professional evaluation by a qualified healthcare provider. This assessment will evaluate the severity of your addiction and provide an individualized treatment plan based on the results. Flexeril overdose occurs when one takes too much of this medication. Overdosing on Flexeril can have very serious consequences, including coma and even death. It is also possible to experience an accidental overdose if you are taking other medications at the same time that could interact with it and cause toxicity.

  • Primary endpoints for both trials were determined by patient-generated data and included global impression of change, medication helpfulness, and relief from starting backache.
  • If a person has an overactive thyroid, heart issues or problems with the liver, Flexeril can be risky and should not be taken.
  • If you cannot swallow the capsule whole, you may open the capsule and sprinkle the contents over one tablespoon of applesauce.
  • This can help keep levels of this drug from building up too much in your body.
  • Adding plans allows you to compare formulary status to other drugs in the same class.

Cyclobenzaprine has mild interactions with at least 221 different drugs. Cyclobenzaprine has moderate interactions with at least 43 different drugs. Secondary endpoints included a physician’s evaluation hydrocodone and flexeril of the presence and extent of palpable muscle spasm. In light of these findings, therapy with FLEXERIL in the elderly should be initiated with a 5 mg dose and titrated slowly upward.

Things to Consider Before Taking Cyclobenzaprine

Observation with cardiac monitoring and observation for signs of CNS or respiratory depression, hypotension, cardiac dysrhythmias and/or conduction blocks, and seizures is necessary. If signs of toxicity occur at any time during this period, extended monitoring is required. Monitoring of plasma drug levels should not guide management of the patient. Dialysis is probably of no value because of low plasma concentrations of the drug. As management of overdose is complex and changing, it is recommended that the physician contact a poison control center for current information on treatment.

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